2610, 2019

Necessary Considerations for Viral Vector Development and Manufacturing

By |October 26th, 2019|Categories: Research & Development|0 Comments

Viral vectors are at the cutting edge of gene therapy, cancer treatment, and vaccine development, but which vector is right for which therapy depends on a great number of factors. Advancements in the last few decades have led to much wider use of viral vectors in gene therapy, vaccines, and [...]

2410, 2019

Syringe Filling at Scale to Deliver on the Increased Demand for Parenteral Product in Pre-Filled Syringes

By |October 24th, 2019|Categories: Manufacturing|0 Comments

Right now, pre-filled syringes are one of the most popular forms of delivery for countless parenteral products, both under hospital conditions and at home. What’s more, their popularity has grown exponentially in recent years, and shows no sign of slowing in the coming decades. However, the ubiquity of parenteral products [...]

2310, 2019

Aseptic Processing of Sterile Drug Products—Current Industry Best Practices

By |October 23rd, 2019|Categories: Manufacturing|0 Comments

Aseptic processing is used in many industries, for many purposes besides the production of sterile drug product. For example, aseptic processing has become the industry standard for handling liquid food products such as milk, fruit juice, and others—not to mention growing in popularity for foods like cottage cheese, vegetable soups, [...]

2109, 2019

Three Essential Considerations When Working With E. Coli Expression Systems

By |September 21st, 2019|Categories: Research & Development|0 Comments

E. coli expression systems involve many variables but are one of the most common and efficient methods for protein expression. E. coli is by far the most popular protein expression platform. The days when pharmaceutical manufacturers had to refine large quantities of plant or animal tissues and fluids into the [...]

1809, 2019

Optimizing the Lyophilization Cycle

By |September 18th, 2019|Categories: Manufacturing|0 Comments

The lyophilization cycle is a key component in the manufacturing process of many pharmaceutical products. Understanding lyophilization requires a basic understanding of sublimation—the process by which a solid transitions directly to a vapor or gaseous state without first passing through a liquid phase. Sublimation is part of the lyophilization cycle, [...]

1609, 2019

The Quickest and Surest Path to Successful Clinical Trial Material Manufacturing

By |September 16th, 2019|Categories: Manufacturing|0 Comments

Clinical trials are an integral part of the drug development process, but successful clinical trials require materials that can be quickly and reliably produced in accordance with the dynamic demands of trial protocols. The manufacture of clinical trial material (CTM) often happens at smaller scale than other contract manufacturing operations, [...]